Human PDLIM5 activation kit by CRISPRa

CAT#: GA107264

PDLIM5 CRISPRa kit - CRISPR gene activation of human PDZ and LIM domain 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PDLIM5
• Locus ID: 10611
• Kit Components:

  GA107264G1, PDLIM5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107264G2, PDLIM5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107264G3, PDLIM5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001011513, NM_001011514, NM_001011515, NM_001011516, NM_001256425, NM_001256426, NM_001256427, NM_001256428, NM_001256429, NM_006457, NR_003257, NR_024179, NR_046186
• Synonyms: ENH; ENH1; L9; LIM
• Summary: This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]