Human AMSH (STAMBP) activation kit by CRISPRa

CAT#: GA107270

STAMBP CRISPRa kit - CRISPR gene activation of human STAM binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: STAMBP
• Locus ID: 10617
• Kit Components:

  GA107270G1, STAMBP gRNA vector 1 in pCas-Guide-CRISPRa

  GA107270G2, STAMBP gRNA vector 2 in pCas-Guide-CRISPRa

  GA107270G3, STAMBP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006463, NM_201647, NM_213622, NM_001353967, NM_001353968, NM_001353969, NM_001353970, NM_001353971, NM_001353972, NM_001353973, NM_001353974, NM_001353975, NM_001353976, NR_148668, NR_148669, NR_148670, NR_148671
• Synonyms: AMSH; MICCAP
• Summary: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]