AMSH (STAMBP) Human Gene Knockout Kit (CRISPR)

CAT#: KN401090

STAMBP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: STAMBP
• Locus ID: 10617
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_006463, NM_201647, NM_213622, NM_001353967, NM_001353968, NM_001353969, NM_001353970, NM_001353971, NM_001353972, NM_001353973, NM_001353974, NM_001353975, NM_001353976, NR_148668, NR_148669, NR_148670, NR_148671
• Synonyms: AMSH; MICCAP
• Summary: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]