Human CELF2 activation kit by CRISPRa

CAT#: GA107307

CELF2 CRISPRa kit - CRISPR gene activation of human CUGBP Elav-like family member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CELF2
• Locus ID: 10659
• Kit Components:

  GA107307G1, CELF2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107307G2, CELF2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107307G3, CELF2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025076, NM_001025077, NM_001083591, NM_006561, NM_001326317, NM_001326318, NM_001326319, NM_001326320, NM_001326321, NM_001326323, NM_001326324, NM_001326325, NM_001326326, NM_001326327, NM_001326328, NM_001326329, NM_001326330, NM_001326331, NM_001326332, NM_001326333, NM_001326334, NM_001326335, NM_001326336, NM_001326337, NM_001326338, NM_001326339, NM_001326340, NM_001326341, NM_001326342, NM_001326343, NM_001326344, NM_001326345, NM_001326346, NM_001326347, NM_001326348, NM_001326349
• Synonyms: BRUNOL3; CUGBP2; ETR-3; ETR3; NAPOR
• Summary: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]