Human C1orf2 (FAM189B) activation kit by CRISPRa

CAT#: GA107337

FAM189B CRISPRa kit - CRISPR gene activation of human family with sequence similarity 189 member B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FAM189B
• Locus ID: 10712
• Kit Components:

  GA107337G1, FAM189B gRNA vector 1 in pCas-Guide-CRISPRa

  GA107337G2, FAM189B gRNA vector 2 in pCas-Guide-CRISPRa

  GA107337G3, FAM189B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001267608, NM_006589, NM_198264
• Synonyms: C1orf2; COTE1
• Summary: This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]