Human WDR4 activation kit by CRISPRa

CAT#: GA107390

WDR4 CRISPRa kit - CRISPR gene activation of human WD repeat domain 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WDR4
• Locus ID: 10785
• Kit Components:

  GA107390G1, WDR4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107390G2, WDR4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107390G3, WDR4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001260474, NM_001260475, NM_001260476, NM_001260477, NM_018669, NM_033661, NM_033662, NR_048535
• Synonyms: TRM82; TRMT82
• Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]