Human Hsp105 (HSPH1) activation kit by CRISPRa

CAT#: GA107408

HSPH1 CRISPRa kit - CRISPR gene activation of human heat shock protein family H (Hsp110) member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HSPH1
• Locus ID: 10808
• Kit Components:

  GA107408G1, HSPH1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107408G2, HSPH1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107408G3, HSPH1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286503, NM_001286504, NM_001286505, NM_006644, NM_001349704
• Synonyms: HSP105; HSP105A; HSP105B; NY-CO-25
• Summary: This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017]