Human PRSS21 activation kit by CRISPRa

CAT#: GA107505

PRSS21 CRISPRa kit - CRISPR gene activation of human serine protease 21

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRSS21
• Locus ID: 10942
• Kit Components:

  GA107505G1, PRSS21 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107505G2, PRSS21 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107505G3, PRSS21 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270452, NM_006799, NM_144956, NM_144957, NR_073012
• Synonyms: ESP-1; ESP1; TEST1; TESTISIN
• Summary: This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]