Human 14-3-3 theta (YWHAQ) activation kit by CRISPRa

CAT#: GA107531

YWHAQ CRISPRa kit - CRISPR gene activation of human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: YWHAQ
• Locus ID: 10971
• Kit Components:

  GA107531G1, YWHAQ gRNA vector 1 in pCas-Guide-CRISPRa

  GA107531G2, YWHAQ gRNA vector 2 in pCas-Guide-CRISPRa

  GA107531G3, YWHAQ gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006826
• Synonyms: 1C5; 14-3-3; HS1
• Summary: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]