Human Cyclin (CCNI) activation kit by CRISPRa

CAT#: GA107541

CCNI CRISPRa kit - CRISPR gene activation of human cyclin I

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCNI
• Locus ID: 10983
• Kit Components:

  GA107541G1, CCNI gRNA vector 1 in pCas-Guide-CRISPRa

  GA107541G2, CCNI gRNA vector 2 in pCas-Guide-CRISPRa

  GA107541G3, CCNI gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006835, NM_001348132, NM_001348133, NM_001348134, NM_001348135, NM_001348136, NM_001348137, NM_001348138, NM_001348139, NM_001348140
• Synonyms: CCNI1; CYC1; CYI
• Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. [provided by RefSeq, Jan 2017]