Human U2AF65 (U2AF2) activation kit by CRISPRa

CAT#: GA107805

U2AF2 CRISPRa kit - CRISPR gene activation of human U2 small nuclear RNA auxiliary factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: U2AF2
• Locus ID: 11338
• Kit Components:

  GA107805G1, U2AF2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107805G2, U2AF2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107805G3, U2AF2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012478, NM_007279
• Synonyms: U2AF65
• Summary: U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]