Human TXNDC4 (ERP44) activation kit by CRISPRa

CAT#: GA108015

ERP44 CRISPRa kit - CRISPR gene activation of human endoplasmic reticulum protein 44

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ERP44
• Locus ID: 23071
• Kit Components:

  GA108015G1, ERP44 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108015G2, ERP44 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108015G3, ERP44 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015051
• Synonyms: PDIA10; TXNDC4
• Summary: This gene encodes a member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. It has an inferred N-terminal signal peptide, a catalytically active thioredoxin (TRX) domain, two TRX-like domains and a C-terminal ER-retention sequence. This protein functions as a pH-regulated chaperone of the secretory pathway and likely plays a role in protein quality control at the endoplasmic reticulum - Golgi interface. [provided by RefSeq, Dec 2016]