Human ANKLE2 activation kit by CRISPRa

CAT#: GA108069

ANKLE2 CRISPRa kit - CRISPR gene activation of human ankyrin repeat and LEM domain containing 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ANKLE2
• Locus ID: 23141
• Kit Components:

  GA108069G1, ANKLE2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108069G2, ANKLE2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108069G3, ANKLE2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015114
• Synonyms: KIAA0692; Lem4; LEMD7; MCPH16
• Summary: This gene encodes a member of the LEM family of inner nuclear membrane proteins. The encoded protein functions as a mitotic regulator through postmitotic formation of the nuclear envelope. Mutations in this gene cause morphology defects in the nuclear envelope and BAF hyperphosphorylation. [provided by RefSeq, Mar 2014]