Human PMPCA activation kit by CRISPRa

CAT#: GA108121

PMPCA CRISPRa kit - CRISPR gene activation of human peptidase, mitochondrial processing alpha subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PMPCA
• Locus ID: 23203
• Kit Components:

  GA108121G1, PMPCA gRNA vector 1 in pCas-Guide-CRISPRa

  GA108121G2, PMPCA gRNA vector 2 in pCas-Guide-CRISPRa

  GA108121G3, PMPCA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282944, NM_001282946, NM_015160
• Synonyms: Alpha-MPP; INPP5E; P-55; SCAR2
• Summary: The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2. [provided by RefSeq, Mar 2016]