Human NOMO1 activation kit by CRISPRa

CAT#: GA108297

NOMO1 CRISPRa kit - CRISPR gene activation of human NODAL modulator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NOMO1
• Locus ID: 23420
• Kit Components:

  GA108297G1, NOMO1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108297G2, NOMO1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108297G3, NOMO1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014287
• Synonyms: Nomo; PM5
• Summary: This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). [provided by RefSeq, Jul 2008]