Human LMOD1 activation kit by CRISPRa

CAT#: GA108547

LMOD1 CRISPRa kit - CRISPR gene activation of human leiomodin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LMOD1
• Locus ID: 25802
• Kit Components:

  GA108547G1, LMOD1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108547G2, LMOD1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108547G3, LMOD1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012134
• Synonyms: 1D; 64kD; D1; SM-LMOD; SMLMOD
• Summary: The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008]