Human TNFAIP8 activation kit by CRISPRa
CAT#: GA108556
TNFAIP8 CRISPRa kit - CRISPR gene activation of human TNF alpha induced protein 8
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | TNFAIP8 |
Locus ID | 25816 |
Kit Components | GA108556G1, TNFAIP8 gRNA vector 1 in pCas-Guide-CRISPRa GA108556G2, TNFAIP8 gRNA vector 2 in pCas-Guide-CRISPRa GA108556G3, TNFAIP8 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001077654, NM_001286813, NM_001286814, NM_001286815, NM_001286817, NM_014350 |
Synonyms | GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2 |
Summary | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. [UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN402729 | TNFAIP8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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