TNFAIP8 Human Gene Knockout Kit (CRISPR)

CAT#: KN402729

TNFAIP8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN402729 is the updated version of KN202729.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol TNFAIP8
Locus ID 25816
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001077654, NM_001286813, NM_001286814, NM_001286815, NM_001286817, NM_014350
Synonyms GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2
Summary Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. [UniProtKB/Swiss-Prot Function]

Other Versions

SKU Description Size Price
GA108556 TNFAIP8 CRISPRa kit - CRISPR gene activation of human TNF alpha induced protein 8
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.