Human DECR2 activation kit by CRISPRa

CAT#: GA108733

DECR2 CRISPRa kit - CRISPR gene activation of human 2,4-dienoyl-CoA reductase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DECR2
• Locus ID: 26063
• Kit Components:

  GA108733G1, DECR2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108733G2, DECR2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108733G3, DECR2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020664
• Synonyms: PDCR; SDR17C1
• Summary: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. [UniProtKB/Swiss-Prot Function]