Human GPSM1 activation kit by CRISPRa

CAT#: GA108742

GPSM1 CRISPRa kit - CRISPR gene activation of human G protein signaling modulator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPSM1
• Locus ID: 26086
• Kit Components:

  GA108742G1, GPSM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108742G2, GPSM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108742G3, GPSM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145638, NM_001145639, NM_001200003, NM_015597
• Synonyms: AGS3
• Summary: G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. This gene encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G-protein signaling systems. The protein contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]