Human VPS41 activation kit by CRISPRa

CAT#: GA108991

VPS41 CRISPRa kit - CRISPR gene activation of human VPS41 subunit of HOPS complex

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VPS41
• Locus ID: 27072
• Kit Components:

  GA108991G1, VPS41 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108991G2, VPS41 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108991G3, VPS41 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014396, NM_080631
• Synonyms: HVPS41; hVps41p; HVSP41
• Summary: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008]