Human IL17B activation kit by CRISPRa

CAT#: GA109060

IL17B CRISPRa kit - CRISPR gene activation of human interleukin 17B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL17B
• Locus ID: 27190
• Kit Components:

  GA109060G1, IL17B gRNA vector 1 in pCas-Guide-CRISPRa

  GA109060G2, IL17B gRNA vector 2 in pCas-Guide-CRISPRa

  GA109060G3, IL17B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317987, NM_014443
• Synonyms: IL-17B; IL-20; NIRF; ZCYTO7
• Summary: The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]