Human PGAP2 activation kit by CRISPRa

CAT#: GA109117

PGAP2 CRISPRa kit - CRISPR gene activation of human post-GPI attachment to proteins 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PGAP2
• Locus ID: 27315
• Kit Components:

  GA109117G1, PGAP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109117G2, PGAP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109117G3, PGAP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145438, NM_001145439, NM_001256235, NM_001256236, NM_001256237, NM_001256238, NM_001256239, NM_001256240, NM_001283038, NM_001283039, NM_001283040, NM_014489, NR_027014, NR_027015, NR_027016, NR_027017, NR_027018, NR_045923, NR_045925, NR_045926, NR_045927, NR_045929, NR_104270, NR_104271, NR_104272, NM_001346397, NM_001346398, NM_001346399, NM_001346400, NM_001346401, NM_001346402, NM_001346403, NM_001346404, NM_001346405, NR_144427, NR_144428, NR_144429, NR_144430
• Synonyms: CWH43-N; FRAG1; HPMRS3; MRT17; MRT21
• Summary: The protein encoded by this gene plays a role in the maturation of glycosylphosphatidylinositol (GPI) anchors on GPI-anchored proteins. Mutations in this gene are associated with an autosomal recessive syndrome characterized by hyperphosphatasia and intellectual disability. [provided by RefSeq, Jul 2017]