PGAP2 Human Gene Knockout Kit (CRISPR)

CAT#: KN413084

PGAP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: PGAP2
• Locus ID: 27315
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001145438, NM_001145439, NM_001256235, NM_001256236, NM_001256237, NM_001256238, NM_001256239, NM_001256240, NM_001283038, NM_001283039, NM_001283040, NM_014489, NR_027014, NR_027015, NR_027016, NR_027017, NR_027018, NR_045923, NR_045925, NR_045926, NR_045927, NR_045929, NR_104270, NR_104271, NR_104272, NM_001346397, NM_001346398, NM_001346399, NM_001346400, NM_001346401, NM_001346402, NM_001346403, NM_001346404, NM_001346405, NR_144427, NR_144428, NR_144429, NR_144430
• Synonyms: CWH43-N; FRAG1; HPMRS3; MRT17; MRT21
• Summary: The protein encoded by this gene plays a role in the maturation of glycosylphosphatidylinositol (GPI) anchors on GPI-anchored proteins. Mutations in this gene are associated with an autosomal recessive syndrome characterized by hyperphosphatasia and intellectual disability. [provided by RefSeq, Jul 2017]