Human BHLHB5 (BHLHE22) activation kit by CRISPRa

CAT#: GA109119

BHLHE22 CRISPRa kit - CRISPR gene activation of human basic helix-loop-helix family member e22

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BHLHE22
• Locus ID: 27319
• Kit Components:

  GA109119G1, BHLHE22 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109119G2, BHLHE22 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109119G3, BHLHE22 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_152414
• Synonyms: Beta3; BHLHB5; CAGL85; TNRC20
• Summary: This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors that regulate cell fate determination, proliferation, and differentiation. A similar protein in mouse is required for the development of the dorsal cochlear nuclei, and is thought to play a role in in the differentiation of neurons involved in sensory input. The mouse protein also functions in retinogenesis. [provided by RefSeq, Oct 2016]