Human Nucleoside Diphosphate Kinase 7 (NME7) activation kit by CRISPRa

CAT#: GA109312

NME7 CRISPRa kit - CRISPR gene activation of human NME/NM23 family member 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NME7
• Locus ID: 29922
• Kit Components:

  GA109312G1, NME7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109312G2, NME7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109312G3, NME7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013330, NM_197972, NR_104229
• Synonyms: CFAP67; MN23H7; NDK 7; NDK7; nm23-H7
• Summary: This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]