Human GLUT8 (SLC2A8) activation kit by CRISPRa

CAT#: GA109360

SLC2A8 CRISPRa kit - CRISPR gene activation of human solute carrier family 2 member 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC2A8
• Locus ID: 29988
• Kit Components:

  GA109360G1, SLC2A8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109360G2, SLC2A8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109360G3, SLC2A8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271711, NM_001271712, NM_014580, NR_073416
• Synonyms: GLUT8; GLUTX1
• Summary: This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]