Human PNPLA8 activation kit by CRISPRa

CAT#: GA109439

PNPLA8 CRISPRa kit - CRISPR gene activation of human patatin like phospholipase domain containing 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PNPLA8
• Locus ID: 50640
• Kit Components:

  GA109439G1, PNPLA8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109439G2, PNPLA8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109439G3, PNPLA8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256007, NM_001256008, NM_001256009, NM_001256010, NM_001256011, NM_015723, N57453
• Synonyms: IPLA2(GAMMA); IPLA2-2; IPLA2G; iPLA2gamma
• Summary: This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2015]