Human Galanin (GAL) activation kit by CRISPRa

CAT#: GA109548

GAL CRISPRa kit - CRISPR gene activation of human galanin and GMAP prepropeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GAL
• Locus ID: 51083
• Kit Components:

  GA109548G1, GAL gRNA vector 1 in pCas-Guide-CRISPRa

  GA109548G2, GAL gRNA vector 2 in pCas-Guide-CRISPRa

  GA109548G3, GAL gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015973
• Synonyms: GAL-GMAP; GALN; GLNN; GMAP
• Summary: This gene encodes a neuroendocrine peptide that is widely expressed in the central and peripheral nervous systems and also the gastrointestinal tract, pancreas, adrenal gland and urogenital tract. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: galanin and galanin message-associated peptide (GMAP). Galanin has diverse physiological functions including nociception, feeding and energy homeostasis, osmotic regulation and water balance. GMAP has been demonstrated to possess antifungal activity and hypothesized to be part of the innate immune system. [provided by RefSeq, Jul 2015]