Human SAR1B activation kit by CRISPRa

CAT#: GA109590

SAR1B CRISPRa kit - CRISPR gene activation of human secretion associated Ras related GTPase 1B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SAR1B
• Locus ID: 51128
• Kit Components:

  GA109590G1, SAR1B gRNA vector 1 in pCas-Guide-CRISPRa

  GA109590G2, SAR1B gRNA vector 2 in pCas-Guide-CRISPRa

  GA109590G3, SAR1B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033503, NM_016103
• Synonyms: ANDD; CMRD; GTBPB; SARA2
• Summary: The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]