Human PHF21A activation kit by CRISPRa

CAT#: GA109736

PHF21A CRISPRa kit - CRISPR gene activation of human PHD finger protein 21A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PHF21A
• Locus ID: 51317
• Kit Components:

  GA109736G1, PHF21A gRNA vector 1 in pCas-Guide-CRISPRa

  GA109736G2, PHF21A gRNA vector 2 in pCas-Guide-CRISPRa

  GA109736G3, PHF21A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001101802, NM_016621, NM_001352025, NM_001352026, NM_001352027, NM_001352028, NM_001352029, NM_001352030, NM_001352031, NM_001352032, NR_147890
• Synonyms: BHC80; BM-006
• Summary: The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]). [supplied by OMIM, Nov 2010]