Human ETS1 associated protein II (TDP2) activation kit by CRISPRa

CAT#: GA109879

TDP2 CRISPRa kit - CRISPR gene activation of human tyrosyl-DNA phosphodiesterase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TDP2
• Locus ID: 51567
• Kit Components:

  GA109879G1, TDP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109879G2, TDP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109879G3, TDP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016614
• Synonyms: AD022; dJ30M3.3; EAP2; EAPII; hTDP2; TTRAP
• Summary: This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]