Human Suppressor of Fused (SUFU) activation kit by CRISPRa
CAT#: GA109940
SUFU CRISPRa kit - CRISPR gene activation of human SUFU negative regulator of hedgehog signaling
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | SUFU |
Locus ID | 51684 |
Kit Components | GA109940G1, SUFU gRNA vector 1 in pCas-Guide-CRISPRa GA109940G2, SUFU gRNA vector 2 in pCas-Guide-CRISPRa GA109940G3, SUFU gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001178133, NM_016169 |
Synonyms | PRO1280; SUFUH; SUFUXL |
Summary | The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN401021 | SUFU - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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