Human Suppressor of Fused (SUFU) activation kit by CRISPRa

CAT#: GA109940

SUFU CRISPRa kit - CRISPR gene activation of human SUFU negative regulator of hedgehog signaling


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol SUFU
Locus ID 51684
Kit Components

GA109940G1, SUFU gRNA vector 1 in pCas-Guide-CRISPRa

GA109940G2, SUFU gRNA vector 2 in pCas-Guide-CRISPRa

GA109940G3, SUFU gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001178133, NM_016169
Synonyms PRO1280; SUFUH; SUFUXL
Summary The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.