Human SNTG1 activation kit by CRISPRa

CAT#: GA110077

SNTG1 CRISPRa kit - CRISPR gene activation of human syntrophin gamma 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNTG1
• Locus ID: 54212
• Kit Components:

  GA110077G1, SNTG1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110077G2, SNTG1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110077G3, SNTG1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001287813, NM_001287814, NM_001321773, NM_001321775, NM_001321776, NM_001321777, NM_001321778, NM_018967, NR_135794, NR_135795, NR_135796, NR_135797, NR_135798
• Synonyms: G1SYN; SYN4
• Summary: The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This family member plays a role in mediating gamma-enolase trafficking to the plasma membrane and in enhancing its neurotrophic activity. Mutations in this gene are associated with idiopathic scoliosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]