Human Pet1 (FEV) activation kit by CRISPRa
CAT#: GA110235
FEV CRISPRa kit - CRISPR gene activation of human FEV transcription factor, ETS family member
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | FEV |
Locus ID | 54738 |
Kit Components | GA110235G1, FEV gRNA vector 1 in pCas-Guide-CRISPRa GA110235G2, FEV gRNA vector 2 in pCas-Guide-CRISPRa GA110235G3, FEV gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_017521 |
Synonyms | HSRNAFEV; PET-1 |
Summary | This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008] |
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Other Versions
SKU | Description | Size | Price |
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KN402917 | FEV - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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