Human PIGG activation kit by CRISPRa

CAT#: GA110329

PIGG CRISPRa kit - CRISPR gene activation of human phosphatidylinositol glycan anchor biosynthesis class G

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIGG
• Locus ID: 54872
• Kit Components:

  GA110329G1, PIGG gRNA vector 1 in pCas-Guide-CRISPRa

  GA110329G2, PIGG gRNA vector 2 in pCas-Guide-CRISPRa

  GA110329G3, PIGG gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127178, NM_001289051, NM_001289052, NM_001289053, NM_001289055, NM_001289057, NM_001345986, NM_001345987, NM_001345988, NM_001345989, NM_001345990, NM_001345991, NM_001345994, NM_017733, NR_110293, NR_144326, NR_144327, NR_144328, NR_144329, NR_144330, NR_144331, NR_144332, NR_144333, NR_144334
• Synonyms: GPI7; LAS21; MRT53; PRO4405; RLGS1930
• Summary: This gene encodes an enzyme involved in glycosylphosphatidylinositol-anchor biosynthesis. The encoded protein, which is localized to the endoplasmic reticulum, is involved in transferring ethanoloamine phosphate to mannose 2 of glycosylphosphatidylinositol species H7 to form species H8. Allelic variants of this gene have been associated with intellectual disability, hypotonia, and early-onset seizures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]