PIGG Human Gene Knockout Kit (CRISPR)

CAT#: KN414539

PIGG - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: PIGG
• Locus ID: 54872
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001127178, NM_001289051, NM_001289052, NM_001289053, NM_001289055, NM_001289057, NM_001345986, NM_001345987, NM_001345988, NM_001345989, NM_001345990, NM_001345991, NM_001345994, NM_017733, NR_110293, NR_144326, NR_144327, NR_144328, NR_144329, NR_144330, NR_144331, NR_144332, NR_144333, NR_144334
• Synonyms: GPI7; LAS21; MRT53; PRO4405; RLGS1930
• Summary: This gene encodes an enzyme involved in glycosylphosphatidylinositol-anchor biosynthesis. The encoded protein, which is localized to the endoplasmic reticulum, is involved in transferring ethanoloamine phosphate to mannose 2 of glycosylphosphatidylinositol species H7 to form species H8. Allelic variants of this gene have been associated with intellectual disability, hypotonia, and early-onset seizures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]