Human CDCA4 activation kit by CRISPRa

CAT#: GA110473

CDCA4 CRISPRa kit - CRISPR gene activation of human cell division cycle associated 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDCA4
• Locus ID: 55038
• Kit Components:

  GA110473G1, CDCA4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110473G2, CDCA4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110473G3, CDCA4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017955, NM_145701
• Synonyms: HEPP; SEI-3/HEPP
• Summary: This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, May 2014]