Human CRTAC1 activation kit by CRISPRa

CAT#: GA110529

CRTAC1 CRISPRa kit - CRISPR gene activation of human cartilage acidic protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CRTAC1
• Locus ID: 55118
• Kit Components:

  GA110529G1, CRTAC1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110529G2, CRTAC1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110529G3, CRTAC1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206528, NM_018058
• Synonyms: ASPIC; ASPIC1; CEP-68
• Summary: This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]