Human C14orf130 (UBR7) activation kit by CRISPRa

CAT#: GA110553

UBR7 CRISPRa kit - CRISPR gene activation of human ubiquitin protein ligase E3 component n-recognin 7 (putative)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBR7
• Locus ID: 55148
• Kit Components:

  GA110553G1, UBR7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110553G2, UBR7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110553G3, UBR7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001100417, NM_018108, NM_175748, NR_038150
• Synonyms: C14orf130; FLJ10483; MGC9518
• Summary: This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul 2016]