Human DRAM (DRAM1) activation kit by CRISPRa

CAT#: GA110712

DRAM1 CRISPRa kit - CRISPR gene activation of human DNA damage regulated autophagy modulator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DRAM1
• Locus ID: 55332
• Kit Components:

  GA110712G1, DRAM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110712G2, DRAM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110712G3, DRAM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018370
• Synonyms: DRAM
• Summary: This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]