Human TRPV6 activation kit by CRISPRa

CAT#: GA110762

TRPV6 CRISPRa kit - CRISPR gene activation of human transient receptor potential cation channel subfamily V member 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRPV6
• Locus ID: 55503
• Kit Components:

  GA110762G1, TRPV6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110762G2, TRPV6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110762G3, TRPV6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014274, NM_018646
• Synonyms: ABP/ZF; CAT1; CATL; ECAC2; HSA277909; LP6728; ZFAB
• Summary: This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015]