Human TRPV6 activation kit by CRISPRa

CAT#: GA110762

TRPV6 CRISPRa kit - CRISPR gene activation of human transient receptor potential cation channel subfamily V member 6


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol TRPV6
Locus ID 55503
Kit Components

GA110762G1, TRPV6 gRNA vector 1 in pCas-Guide-CRISPRa

GA110762G2, TRPV6 gRNA vector 2 in pCas-Guide-CRISPRa

GA110762G3, TRPV6 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_014274, NM_018646
Synonyms ABP/ZF; CAT1; CATL; ECAC2; HSA277909; LP6728; ZFAB
Summary This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.