Human Neurabin 1 (PPP1R9A) activation kit by CRISPRa

CAT#: GA110817

PPP1R9A CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory subunit 9A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP1R9A
• Locus ID: 55607
• Kit Components:

  GA110817G1, PPP1R9A gRNA vector 1 in pCas-Guide-CRISPRa

  GA110817G2, PPP1R9A gRNA vector 2 in pCas-Guide-CRISPRa

  GA110817G3, PPP1R9A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166160, NM_001166161, NM_001166162, NM_001166163, NM_017650
• Synonyms: Neurabin-I; NRB1; NRBI
• Summary: This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]