Human LIMS2 activation kit by CRISPRa

CAT#: GA110877

LIMS2 CRISPRa kit - CRISPR gene activation of human LIM zinc finger domain containing 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LIMS2
• Locus ID: 55679
• Kit Components:

  GA110877G1, LIMS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110877G2, LIMS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110877G3, LIMS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136037, NM_001161403, NM_001161404, NM_001256542, NM_017980, NR_027823
• Synonyms: LGMD2W; PINCH-2; PINCH2
• Summary: This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]