Human RIOK2 activation kit by CRISPRa

CAT#: GA110964

RIOK2 CRISPRa kit - CRISPR gene activation of human RIO kinase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RIOK2
• Locus ID: 55781
• Kit Components:

  GA110964G1, RIOK2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110964G2, RIOK2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110964G3, RIOK2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001159749, NM_018343
• Synonyms: RIO2
• Summary: Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its catalytic activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA. [UniProtKB/Swiss-Prot Function]