Human Pannexin 2 (PANX2) activation kit by CRISPRa

CAT#: GA111213

PANX2 CRISPRa kit - CRISPR gene activation of human pannexin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PANX2
• Locus ID: 56666
• Kit Components:

  GA111213G1, PANX2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111213G2, PANX2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111213G3, PANX2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001160300, NM_052839, NR_027691
• Synonyms: hPANX2; PX2
• Summary: The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]