Human PLSCR4 activation kit by CRISPRa

CAT#: GA111360

PLSCR4 CRISPRa kit - CRISPR gene activation of human phospholipid scramblase 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLSCR4
• Locus ID: 57088
• Kit Components:

  GA111360G1, PLSCR4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111360G2, PLSCR4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111360G3, PLSCR4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001128304, NM_001128305, NM_001128306, NM_001177304, NM_020353, NR_033438, NR_033439
• Synonyms: TRA1
• Summary: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. [UniProtKB/Swiss-Prot Function]