Human Zinc finger MIZ domain containing protein 1 (ZMIZ1) activation kit by CRISPRa

CAT#: GA111428

ZMIZ1 CRISPRa kit - CRISPR gene activation of human zinc finger MIZ-type containing 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZMIZ1
• Locus ID: 57178
• Kit Components:

  GA111428G1, ZMIZ1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111428G2, ZMIZ1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111428G3, ZMIZ1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020338
• Synonyms: hZIMP10; MIZ; RAI17; TRAFIP10; ZIMP10
• Summary: This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]