Human MAVS activation kit by CRISPRa

CAT#: GA111544

MAVS CRISPRa kit - CRISPR gene activation of human mitochondrial antiviral signaling protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAVS
• Locus ID: 57506
• Kit Components:

  GA111544G1, MAVS gRNA vector 1 in pCas-Guide-CRISPRa

  GA111544G2, MAVS gRNA vector 2 in pCas-Guide-CRISPRa

  GA111544G3, MAVS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206491, NM_020746, NR_037921, NR_037922
• Synonyms: CARDIF; IPS-1; IPS1; VISA
• Summary: This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]