Human MTUS1 activation kit by CRISPRa

CAT#: GA111547

MTUS1 CRISPRa kit - CRISPR gene activation of human microtubule associated scaffold protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MTUS1
• Locus ID: 57509
• Kit Components:

  GA111547G1, MTUS1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111547G2, MTUS1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111547G3, MTUS1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001924, NM_001001925, NM_001001927, NM_001001931, NM_001166393, NM_001330470, NM_020749, NM_001363057, NM_001363059, NM_001363061, NM_001363062, NM_001363058, NM_001363060, NR_156437
• Synonyms: ATBP; ATIP; ICIS; MP44; MTSG1
• Summary: This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]